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Dry Ice Shipping: Biologics for Precision Medicine Research

Royale International’s bio-logistics experts provide documentation and customs clearance support for biotech companies.

Royale International’s bio-logistics experts provide documentation and customs clearance support for biotech companies.   Our Industry Experts offer dry ice shipping services for biological products worldwide.   The case below exhibits how Royale handled a request to ship vials of human plasma.


How does human plasma support biotechnological research?

A Singaporean research lab requested a shipment of cryovials with biological (i.e., plasma) samples from a university lab in Hong Kong to their office in Singapore.   Plasma contains biomarkers that reflect the physiological and pathological conditions of a body.   Insight derived from plasma can help biotech companies identify and develop medicine that could target conditions or illnesses that the patient is experiencing or will experience.   Ultimately, this shipment supported the research lab’s study in genomics and supported the global advancement of precision healthcare.

What are common challenges for plasma via dry ice shipping?

The research lab requested the shipment under dry ice temperatures (i.e., -80˚C) to prevent the proteins and other biomarkers from breaking.   In addition to the requested temperature, monitoring the shock and motion of the cryovials was paramount.  These fragile equipment requires careful handling.   

Finally, human plasma is classified as biological material.   Hence, documentation for these products can be extensive and must be filled in by organizations with expertise & experience.   Despite being non-infectious, the courier will be fined if not declared properly. 

How did Royale’s dry ice shipping services secure the plasma samples?

Our quality-driven temperature-controlled logistics services include validated equipment and professional on-board medical couriers that ensure the safe and secure transport of cryovials.   Through our 30+ logistics expertise, our experts offered auxiliary logistics services that supported seamless transit. 

  • The requestor assorted and loaded about 500 cryovials of plasma into compartment grids and into six Intelsius Biotherm cryoboxes  
  • In addition to packing dry ice in the boxes, Royale included our high-end data loggers to monitor temperature, shock, and other metrics. 
  • Royale’s Industry Experts prompted the requestors to register their Importer of Record (IOR) with Singapore Customs whilst Royale’s team provided documentation support and retrieved licenses for customs clearance 
  • Then, the courier was able to declare and provide the pre-filled documents to clear the shipment with ease 
  • Finally, the research lab received the cryovials shortly after. 
Royale International's Life Science Global Network

Royale International is a single source logistics provider that secures temperature-controlled shipments. Our logistics solutions are quality-driven and leverage our global infrastructure to advance the biotechnology and medical healthcare sectors. 

Learn more about our medical On-Board Courier (OBC) network. Read through our previous article.

Want to speak to our Life Sciences experts about a bio-logistics solution? Send an email to lifesciences@royaleinternational.com 

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